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KMID : 1103720090610010023
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Journal of the Korean Society of Radiology
2009 Volume.61 No. 1 p.23 ~ p.29
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Endovascular Management of Deep venous Thrombosis of Lower Extremity in Patients with Malignant Disease
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Kim Jae-Kyu
Jeong Su-Jin
Chang Nam-Kyu
Han Seung-Min
Kang Heoung-Keun
Choi Soo-Jin-Na
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Abstract
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Purpose: To evaluate the efficacy of endovascular management of lower extremity deep vein thrombosis (DVT) in patients with malignant disease.
Materials and Methods: Between January 2002 and January 2008, six consecutive patients (5 male and 1 female, mean age-65 years) with lower extremity DVT and malignant disease underwent endovascular management. The duration of symptoms lasted 4-120 days (mean-31 days; 20 days or less in four patients and more than 20 days in two). A catheter-directed thrombolysis was performed via the ipsilateral popliteal vein or common femoral vein, used alone or combined with a percutaneous mechanical thrombectomy. Angioplasty or stent placement was performed in residual stenosis or occlusion of the vein. The follow-up period lasted 1-14 months (mean 7.6 months) and was performed via a color Doppler ultrasonography or computed tomographic venography.
Results: Technical success and relief from symptoms was achieved within two days was achieved in five patients. Minor hemorrhagic complications occurred in two cases: hematuria and a hematoma at the puncture site. Upon follow-up, a recurrent DVT occurred in three patients as well as a patent venous flow in two. One patient died within 1 month due to a metastatic mediastinal lymphadenopathy.
Conclusion: Endovascular management of the lower extremity DVT is effective for quickly eliminating a thrombus, relieving symptoms, and decreasing hemorrhagic complications in patients with malignant disease.
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KEYWORD
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Neoplasm, Venous thrombosis, Interventional procedure
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